HERBAL MEDICINE: BLOOD CANCER CELL SUICIDE STYLE
Piece life after retired remains mirage for Syafril Roy. Result of inspection of health in RS Persahabatan, Rawamangun Jakarta Timur, shows that he got blood cancer and diabetes mellitus. Imagines death likely presents in the eyes. consumption of Phalaeria Macrocarpa regularly becomes healing fulcrums Syahril.
Initially leukocyte rate bounces up until 60000, and always rising until 100000. sugar rate in blood 340 mmHg. The man 65 years frequently feels headache. Cool sweat flows down. Suggestion to take back bone marrow is refused. One month after routine drinks ingredient Phalaeria Macrocarpa number leukocyte reduces to 74000. repair of the condition also is followed stable of sugar rate in blood.
The healing not just incident. From back of wall laboratories, Prof Dr Akio Mimura from Biotechnology Department, University Yamanashi, Japan, successfully opens clue. He identifies anticarcinogenetic active compound from fruit and Phalaeria Macrocarpa cochlea, proven can depress growth of cell leukemia in vitro. Anticipated the compound can induce process apoptosis.
According To Dr Ahkam Subroto, biotechnology researcher LIPI, apoptosis is an death active program of a real normal cell Biotechnology ”in laymen language usually is conceived of suicide process ( suicide),” says Ahkam.
SuicideApoptosis is keyword in cancer healing. At cancer patient, cells do not die and continuous multiplies itself. It cause by two things: deviation in process of bisection or trouble at system apoptosis. Akio believes, Phalaeria Macrocarpa contains mitosis resistor compound and triggers process to suicide/apoptosis at cancer cells. Mean member of Thymelaeaceae set of cancer cell to do suicide.
That happy news goes along with research Drs. Vivi Lisdawati Apt Msi, researcher from Litbang department of public health. “Positive indication Phalaeria Macrocarpa because have positive indication the character of sitoksis to break cancer cell,” says Vivi Alumnus pharmacy department Indonesia university. Same as Akio, Vivi also does work of indium vintro, applies mouse as experiment animal. The difference is she applies cell L1210 isolated from spleen. Apparently, 50% cell leukemia in the animal spleen is hampering after dropped by extraction Phalaeria Macrocarpa good news to leukemia patient and other cancer. Research of course done at blood cancer. However, did not close applicable possibility at other cancer disease if process apoptosis is suicide happened.
Apparently besides anticancer, Phalaeria Macrocarpa also functioning as antioxidant and ant diabetes. Research of Phalaeria Macrocarpa as antioxidant also does by akio. He successfully finds fact, in 100 Phalaeria Macrocarpa kernel grams there is mean 374 compound magnesium antioxidant. This higher rate compared to antioxidant rate from various tea types, herb.
Antioxidant is not directly correlate to ant cancer. “Antioxidant stands in free radical arrest. Cancer relates to life style and complicated factor,” says Ahkam. However, heaping of free radical can become one of cancer stimulate. here the role of antioxidant as preventive for free radical. Besides anticancer and usage antioxidant of Phalaeria Macrocarpa as anti diabetes also attract enthusiasm of the researchers. Research in LIPI has proved, Phalaeria Macrocarpa extract hamper glycosidase enzyme job activity in indium vintro.
Glycosidase enzyme is enzyme contributing in distorting of carbohydrate becomes glucose. With stop of the enzyme activity, hence glucose rate in manageable blood in normal boundary. For therapy world of Phalaeria Macrocarpa, research is valuable finding. The way towards scientific verification increasingly wide open for phalaeria macrocarpa.